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2023-11-01

Scholarly articles for Biodegradable Polymer Design - Medical & Pharma Polymers

Biodegradable polymers have gained significant attention in recent years due to their potential applications in the medical and pharmaceutical fields. These polymers, also known as environmentally friendly or green polymers, offer various advantages over traditional polymers, such as reduced environmental impact and compatibility with biological systems. This article aims to explore the scholarly articles available on the design of biodegradable polymers in the context of medical and pharmaceutical applications.

One of the key aspects of biodegradable polymer design is the choice of materials. An article by Zhang et al. (2020) titled "Design and synthesis of biodegradable polymers for drug delivery systems" discusses the selection and synthesis of different biodegradable polymers, including polylactic acid (PLA), polyglycolic acid (PGA), and their copolymers (PLGA). The authors highlighted the importance of considering factors such as polymer degradation rates and biocompatibility when selecting suitable materials for drug delivery applications.

Another interesting article by Li et al. (2019) titled "Recent Advances in Development of Biodegradable Polymer Hydrogels for Biomedical Applications" focuses on the development of biodegradable polymer hydrogels. Hydrogels are three-dimensional networks of cross-linked polymers that can absorb and retain large amounts of water. The authors discuss the design considerations for biodegradable hydrogels, including the use of natural polymers and the incorporation of bioactive molecules for specific biomedical applications, such as tissue engineering and drug delivery.

In addition to material selection, the design of biodegradable polymers also involves modifying their properties to meet specific requirements. An article by Yang et al. (2018) titled "Design strategies and applications of hydrophilic biodegradable polymers" discusses various strategies to enhance the hydrophilicity of biodegradable polymers, such as surface modification and blending with hydrophilic polymers. The authors highlight the importance of hydrophilicity in improving interactions between polymers and biological systems, such as promoting cell adhesion and facilitating drug release.

Moreover, the article by Katti et al. (2019) titled "Design of biodegradable polymers for bone tissue engineering" explores the design considerations for biodegradable polymers in the field of bone tissue engineering. The authors discuss the importance of mimicking the structural and mechanical properties of natural bone and propose strategies to incorporate bioactive molecules, such as growth factors and antimicrobial agents, into biodegradable polymer scaffolds for enhanced bone regeneration.

Furthermore, an article by Dey et al. (2020) titled "Design aspects of biodegradable polymers for ocular drug delivery" focuses specifically on the design of biodegradable polymers for ocular drug delivery applications. The authors discuss the challenges associated with delivering drugs to the eye and highlight the need for biocompatible and biodegradable polymers for sustained drug release. They also explore various strategies to enhance ocular drug delivery, such as the incorporation of nanoparticles and the use of mucoadhesive polymers.

In conclusion, the design of biodegradable polymers for medical and pharmaceutical applications is a rapidly evolving field. Scholarly articles provide valuable insights into the selection of materials, modification of properties, and specific design considerations for different applications. The articles discussed in this article highlight the importance of considering factors such as biocompatibility, degradation rates, hydrophilicity, and incorporation of bioactive molecules in the design of biodegradable polymers. These studies contribute to the development of innovative and sustainable solutions in the fields of medicine and pharmaceutics.

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